Journal of Advanced Clinical and Research Insights


Dengue fever, a revisit of the virus associated hemophagocytic syndrome

K. R. Chatura
[Year:2017] [Month:September-October] [Volume:4 ] [Number:5] [Pages No:143–143] [No. of Hits: 744]
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  • [Abstract]
  • [DOI : 10.15713/ins.jcri.179]


Hemophagocytic lymphohistiocytosis (HLH) is a result of uncontrolled macrophage activation with prominent phagocytosis of platelets, erythrocytes, and lymphocytes, and hematopoietic precursors. Attempt should be made to establish or rule out HLH in patients presenting with fever, multisystem inflammation, and varying degrees of unexplained pancytopenia. Apart from EBV, dengue infection, especially in epidemics, has emerged as an important cause of HLH. Early recognition of infection-associated HLH in the tropical Asian populations should stimulate a search for common infections, and early institution of specific treatment and aggressive supportive care, which is essential for reducing morbidity and mortality.


Aesthetics of hair: A sociodemographic study

Mamatha S. Kusagur, N. Asifa, Suga Reddy
[Year:2017] [Month:September-October] [Volume:4 ] [Number:5] [Pages No:144–146] [No. of Hits: 728]
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  • [Abstract]
  • [DOI : 10.15713/ins.jcri.180]


Background and Objective: As the saying goes that “hair in fact is probably the bane of most women’s lives.” Hair care aesthetics is concerned with process of beautification of hair. The current perspective in hair care is not just concerned with cleansing, but the focus has been shifted to prevent hair damage at molecular level. The objective of this study was to correlate the use of various hair cares by women depending on various sociodemographic strata.

Design and Setting: A cross-sectional survey was conducted on 100 females who attended Dermatology Outpatient Department at a Tertiary and Primary Care Centre, Davangere, Karnataka, India open to the general public.

Materials and Methods: A pre-structured questionnaire about hair care products and cleansing was used to randomly assess 100 women.

Results: In our study, 100 females were evaluated in age group of 11-60 years and participants were explained the purpose of the study, we found that about 51% women cleansed their hair once a week. Major cleanser was shampoos used by 78% and soap nut was the least used cleanser in 2%. Hair conditioners were used by 27%. 74% women used hair oil once a week. Hair gel was used by 12%, 14% women used hair sprays. 16% women had colored there hair atleast once in there life time. 25% used hair colors for graying of hair. Branded and special hair care products were used most commonly in women of high socioeconomic status. Middle-class women used shampoos most commonly and cleansed hair once a week. Soap nut and no cleanser were more commonly used by women of low socioeconomic status.

Conclusion: Women consider hair as vital part of there body and trichologists play a focal role in addressing there queries with regard to various cleansers and branded hair care products.

Keywords: Conditioners, hair care, hair cleansing, shampoos

How to cite this article: Kusagur MS, Asifa N, Reddy S. Aesthetics of hair: A sociodemographic study. J Adv Clin Res Insights 2017;4:144-146.

Received 28 July 2017;

Accepted 29 August 2017


Awareness of zinc toxicity in denture adhesives among dental practitioners in Puducherry - A cross-sectional study

Varsha Murthy, Vineela Katam Reddy, S. Vidyalakshmi
[Year:2017] [Month:September-October] [Volume:4 ] [Number:5] [Pages No:147–151] [No. of Hits: 1421]
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  • [DOI : 10.15713/ins.jcri.181]


Background: Denture adhesives should never be used as a solution for ill-fitting dentures on a long-term basis owing to zinc overdose and its deleterious effects. Dentists need to be made aware of the consequences of denture adhesives overusage so that they can dissipate the same information to the patients. Early detection and patient education may help in a reversal of symptoms by withdrawing the usage of denture adhesives or treating with copper supplementation.

Aim: The aim of the study was to assess the awareness of dentist in Puducherry regarding the effects of zinc toxicity.

Materials and Methods: This cross-sectional questionnaire study was conducted on 64 dentists from Puducherry. They were requested to complete the comprehensive self-administered questionnaire regarding their awareness about denture adhesives.

Statistical Analysis used: Means and percentages were calculated using Statistical Package for the Social Sciences 13.01 program.

Results and Conclusions: It was found that dentists knowledge was limited regarding the harmful effects of denture adhesives, thereby leading to misdiagnosis of the toxic symptoms. Dentists are in a position to prevent it early by educating patients directly or using social media such as radio, television, or awareness camps on the use of denture adhesives and to detect early signs of copper deficiency in patients who may be using zinc-containing denture adhesive to excess.

Keywords: Awareness, denture adhesives, questionnaire, zinc toxicity

How to cite this article: Murthy V, Reddy VK, Vidyalakshmi S. Awareness of zinc toxicity in denture adhesives among dental practitioners in Puducherry - A cross-sectional study. J Adv Clin

Res Insights 2017;4:147-151.

Received: 20 July 2017;

Accepted: 23 August 2017


Hematological and cytomorphometric assessment in recurrent aphthous minor - A comparative study

M. G. Madhura, Lipika Kansal, B. Veerendra Kumar, Mahamad Azam
[Year:2017] [Month:September-October] [Volume:4 ] [Number:5] [Pages No:152–157] [No. of Hits: 1132]
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  • [DOI : 10.15713/ins.jcri.182]


Background: Recurrent aphthous stomatitis (RAS) is the common oral disease, characterized by the development of painful, recurring solitary or multiple ulcerations of the oral mucosa. There is no single satisfactory tool for diagnosis of RAS. In addition, there is a paucity of reports on cytomorphometric features in RAS.

Aims and Objectives: The current study had aimed at assessing cytomorphometric features in RAS minor patients and in healthy volunteers, keeping the baseline parameters of complete blood cell count. The objectives were to assess and compare cytopathological and cytomorphometric features in RAS minor and normal individuals.

Materials and Methods: Prospective study sample had comprised 15 cases of RAS minor and 15 of healthy volunteers. The complete blood cell count was performed; oral smears were prepared and were stained with Papanicolaou stain from all study subjects. Cytomorphometric parameters were compared between RAS minor and healthy volunteers. Student’s t-test and SPSS 15.0 software were used for statistical analysis.

Results: On comparison, significant changes in nuclear area and in cell diameter were evident between RAS minor patients and healthy volunteers.

Conclusion: Cytomorphometric analysis may be considered as a valuable adjunct in the diagnosis of RAS minor.

Key words: Cell area, cell diameter, complete blood cell count, nuclear area, nuclear diameter, recurrent aphthous stomatitis minor

How to cite this article: Madhura MG, Kansal L, Kumar BV, Azam M. Hematological and cytomorphometric assessment in recurrent aphthous minor - A comparative study. J Adv Clin Res Insights 2017;4:152-157.

Received: 22 July 2017;

Accepted: 23 August 2017


Comparison of oral health status among pregnant and non-pregnant women residing in Raichur district

K. M. Parveen Reddy, Santosh Hunasgi, Anila Koneru, Rudraraju Amrutha, Vardendra Manvikar
[Year:2017] [Month:September-October] [Volume:4 ] [Number:5] [Pages No:158–161] [No. of Hits: 991]
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  • [DOI : 10.15713/ins.jcri.183]


Background: The physical alterations that happen throughout the pregnancy may amplify a woman’s vulnerability to oral infections, including periodontal disease, and may damage the body’s capability to uphold the soft tissues in the mouth.

Aims and Objectives: The aim of the present study is to consider the oral health status of pregnant women in the age group of 18-35 years in Raichur.

Materials and Methods: A total of 75 pregnant and 75 non-pregnant women in selected age group at the Outpatient Department of a Navodaya Medical Hospital, Raichur, over a period of 6 months were evaluated for oral health status by various indices including decayed, missing, and filled teeth, oral hygiene index-simplified (OHI-S), gingival index (GI), and Russell’s periodontal index (PI). Inclusion and exclusion criteria are healthy pregnant women reporting for antenatal checkup were preferred for study. Study group with systemic diseases such as hypertension, severe anemia, and diabetes mellitus, were expelled. The results of different indices were tabulated and statistically analyzed using unpaired t-test.

Results: The occurrence of dental caries in pregnant women was slightly higher; OHI-S value was considerably superior in pregnant women than that of non-pregnant women. Likewise, PI was also extensively higher in pregnant women. GI showed mild-to-severe gingivitis in pregnant women. However, control group showed predominantly mild gingivitis.

Conclusion: In the current study, the oral hygiene among pregnant women was evident by oral hygiene index and PI, which was statistically noteworthy; however, there was a slight increase in dental caries in pregnant women than the control group. This suggests an inferior oral health of pregnant women, which in turn can reflect on the overall health of fetus. This might possibly affect the birth outcomes, and hence, a mother’s oral health grade is essential to keep the general well-being of the child. Each pregnant woman must be specified with directions to stay up the oral hygiene and persuade their appointment to the dentist.

Key words: Gingival index, oral hygiene index, periodontal index, pregnancy, Raichur

How to cite this article: Reddy KMP, Hunasgi S, Koneru A, Amrutha R, Manvikar V. Comparison of oral health status among pregnant and non-pregnant women residing in Raichur district. J Adv Clin Res Insights 2017;4:158-161.

Received: 02 July 2017;

Accepted: 13 August 2017


Oral biopsy in general dental practice

Santosh Hunasgi, Anila Koneru, Vardendra Manvikar, Rudraraju Amrutha, K. M. Parveen Reddy
[Year:2017] [Month:September-October] [Volume:4 ] [Number:5] [Pages No:162–165] [No. of Hits: 2342]
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  • [Abstract]
  • [DOI : 10.15713/ins.jcri.184]


Proper management of a patient with any oral lesion begins by means of a precise diagnosis. The existing golden criterion for identification is the histopathologic assessment of a tissue biopsy of the doubtful lesion. This is mainly depending on the clinician undertaking a suitable biopsy and providing sufficient medical information, and on the pathologist accurately interprets the biopsy result. Thus, this article focuses on the procedures to undertake biopsy in general dental practice.

Key words: Biopsy, complications, punch, procedure, transport

How to cite this article: Hunasgi S, Koneru A, Manvikar V, Amrutha R, Reddy KMP. Oral biopsy in general dental practice. J Adv Clin Res Insights 2017;4:162-165.

Received: 10 July 2017;

Accepted: 14 August 2017


Fallopian tube pathology – New findings: A review

K. R. Chatura, M. Bhargavi
[Year:2017] [Month:September-October] [Volume:4 ] [Number:5] [Pages No:166–169] [No. of Hits: 4628]
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  • [Abstract]
  • [DOI : 10.15713/ins.jcri.185]


Pathology of fallopian tube, a small organ, is now emerging as a center of interest in gynecological pathology. Non-neoplastic and neoplastic lesions with importance on the emerging tubal serous carcinoma literature are reviewed to emphasize, in women with family history of carcinoma, the necessity of careful examination of fallopian tube.

Keywords: Fallopian tube, p53, serous carcinoma

How to cite this article: Chatura KR, Bhargavi M. Fallopian tube pathology - New findings: A review. J Adv Clin Res Insights 2017;4:166-169.

Received: 01 July 2017;

Accepted: 17 August 2017